缺乏睡眠的人易健忘

张贴于 October 22, 2009 – 7:18 pm | 作者是 黄德峻 |

美国神经学家发现不睡觉的人记忆力比较差。不够睡的人脑中处理情景记忆(也就是时间、地点、物件、人物的记忆)的部分中的某种分子会被破坏。科学家们在老鼠身上做出了实验,他们发现原来缺乏睡眠的老鼠脑力较少某种叫做cAMP的分子,而cAMP负责管理记忆处理基因的活动。而那些缺乏睡眠的老鼠脑中也多出了压抑cAMP的酶——PDE4A5。

Neuroscientists studying rodents and humans have found that sleep deprivation interrupts the storage of episodic memories: information about who, what, when, and where. To lay down these memories, neurons in our brains form new connections with other neurons or strengthen old ones. This rewiring process, which occurs over a period of hours, requires a rat’s nest of intertwined molecular pathways within neurons that turn genes on and off and fine-tune how proteins behave.

—— ScienceNOW: Why Sleepyheads Forget

常常熬夜温习功课,或者考试最后一分钟才点夜灯啃书的人,你们的记忆力可能比一般人还差。科学家希望日后能制造出可以压抑PDE4A5的药物,让cAMP正常活动,来提高记忆效率。

[via Nerdy Science Blog]

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